Storage Conditions
-20°C/1 year
Applications
ELISA
IF
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human p44 MAPK. AA range:161-210
Subcellular Location
Cytoplasm . Nucleus. Membrane, caveola . Cell junction, focal adhesion . Autophosphorylation at Thr-207 promotes nuclear localization (PubMed:19060905). PEA15-binding redirects the biological outcome of MAPK3 kinase-signaling by sequestering MAPK3 into th
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
5595
Observed Band
45kD
Other Name
ERK-1
ERK1
ERT2
Extracellular signal-regulated kinase 1
Insulin-stimulated MAP2 kinase
MAPK 3
MAPK3
MAP kinase 3
MAP kinase isoform p44
Microtubule-associated protein 2 kinase
Mitogen-activated protein kinase 3
PRKM3
p
p44-MAPK
Background
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, a