Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
WB
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human XPF. AA range:801-850
Subcellular Location
Nucleus . Chromosome . Localizes to sites of DNA damage. .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Mouse
Human Gen
2072
Observed Band
103kD
Other Name
DNA excision repair protein ERCC-4
DNA repair endonuclease XPF
DNA repair protein complementing XP-F cells
ERCC4
ERCC11
XPF
Xeroderma pigmentosum group F-complementing protein
DNA repair endonuclease XPF
DNA repair protein complementing XP-F cells
ERCC4
ERCC11
XPF
Xeroderma pigmentosum group F-complementing protein
Background
The protein encoded by this gene forms a complex with ERCC1 and is involved in the 5' incision made during nucleotide excision repair. This complex is a structure specific DNA repair endonuclease that interacts with EME1. Defects in this gene are a cause