Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human HER3. AA range:1191-1240
Subcellular Location
Single-pass type I membrane protein.
[Isoform 1]: Cell membrane
[Isoform 2]: Secreted.
[Isoform 1]: Cell membrane
[Isoform 2]: Secreted.
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
2065
Observed Band
148kD
Other Name
ERBB3
HER3
Proto-oncogene-like protein c-ErbB-3
Receptor tyrosine-protein kinase erbB-3
Tyrosine kinase-type cell surface receptor HER3
HER3
Proto-oncogene-like protein c-ErbB-3
Receptor tyrosine-protein kinase erbB-3
Tyrosine kinase-type cell surface receptor HER3
Background
This gene encodes a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound protein has a neuregulin binding domain but not an active kinase domain. It therefore can bind this ligand but not convey th