Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human p50 Dynamitin. AA range:341-390
Subcellular Location
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Membrane
Peripheral membrane protein .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
10540
Observed Band
50kD
Other Name
50 kDa dynein-associated polypeptide
DCTN-50
DCTN2
DCTN50
Dynactin complex 50 kDa subunit
Dynactin subunit 2
p50 dynamitin
Background
This gene encodes a 50-kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, in