Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
IF: 1:50-200 Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
Synthesized peptide derived from DRP1 . at AA range: 580-660
Subcellular Location
Cytoplasm, cytosol. Golgi apparatus. Endomembrane system
Peripheral membrane protein. Mitochondrion outer membrane
Peripheral membrane protein. Peroxisome. Membrane, clathrin-coated pit . Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane . Mainly cytosolic. Recruited by RALA and RALBP1 to mitochondrion during mitosis (PubMed:21822277). Translocated to
Peripheral membrane protein. Mitochondrion outer membrane
Peripheral membrane protein. Peroxisome. Membrane, clathrin-coated pit . Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane . Mainly cytosolic. Recruited by RALA and RALBP1 to mitochondrion during mitosis (PubMed:21822277). Translocated to
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
10059
Observed Band
80kD
Other Name
DLP1
DNM1L
DRP1
DVLP
Dnm1p/Vps1p-like protein
Dymple
Dynamin-1-like protein
Dynamin-like protein
Dynamin-like protein 4
Dynamin-like protein IV
Dynamin-rela
Dynamin family member proline-rich carboxyl-terminal domain less
HdynIV
DNM1L
DRP1
DVLP
Dnm1p/Vps1p-like protein
Dymple
Dynamin-1-like protein
Dynamin-like protein
Dynamin-like protein 4
Dynamin-like protein IV
Dynamin-rela
Dynamin family member proline-rich carboxyl-terminal domain less
HdynIV
Background
This gene encodes a member of the dynamin superfamily of GTPases. The encoded protein mediates mitochondrial and peroxisomal division, and is involved in developmentally regulated apoptosis and programmed necrosis. Dysfunction of this gene is implicated i