Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
WB
IF
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human TNFRSF10A. AA range:401-450
Subcellular Location
Cell membrane
Single-pass type I membrane protein . Membrane raft . Cytoplasm, cytosol . Palmitoylation is required for association with membranes. .
Single-pass type I membrane protein . Membrane raft . Cytoplasm, cytosol . Palmitoylation is required for association with membranes. .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Monkey
Monkey
Human Gen
8797
Observed Band
50kD
Other Name
APO2
CD antigen CD261
DR4
Death receptor 4
TNF-related apoptosis-inducing ligand receptor 1
TNFRSF10A
TRAIL-R1
TRAILR1
TRAIL receptor 1
Tumor necrosis factor receptor superfamily member 10A
CD antigen CD261
DR4
Death receptor 4
TNF-related apoptosis-inducing ligand receptor 1
TNFRSF10A
TRAIL-R1
TRAILR1
TRAIL receptor 1
Tumor necrosis factor receptor superfamily member 10A
Background
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL), and thus transduces cell death signal and induces cell apoptosis. Studies