Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human DNA-PK. AA range:4061-4110
Subcellular Location
Nucleus . Nucleus, nucleolus .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Mouse
Human Gen
5591
Observed Band
450kD
Other Name
DNA-PK catalytic subunit
DNA-PKcs
DNA-dependent protein kinase catalytic subunit
DNPK1
HYRC
HYRC1
PRKDC
p460
DNA-PKcs
DNA-dependent protein kinase catalytic subunit
DNPK1
HYRC
HYRC1
PRKDC
p460
Background
This gene encodes the catalytic subunit of the DNA-dependent protein kinase (DNA-PK). It functions with the Ku70/Ku80 heterodimer protein in DNA double strand break repair and recombination. The protein encoded is a member of the PI3/PI4-kinase family.[pr