Storage Conditions
-20°C/1 year
Applications
ELISA
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
Synthesized peptide derived from DNA Ligase III . at AA range: 110-190
Subcellular Location
[Isoform 1]: Mitochondrion . Contains an N-terminal mitochondrial transit peptide. .
[Isoform 2]: Mitochondrion . Contains an N-terminal mitochondrial transit peptide. .
[Isoform 3]: Nucleus . Lacks the N-terminal mitochondrial transit peptide. .
[Isoform 4]: Nucleus . Lacks the N-terminal mitochondrial transit peptide. .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
3980
Observed Band
100kD
Other Name
DNA ligase 3
DNA ligase III
LIG3
Polydeoxyribonucleotide synthase [ATP] 3
Background
This gene is a member of the DNA ligase family. Each member of this family encodes a protein that catalyzes the joining of DNA ends but they each have a distinct role in DNA metabolism. The protein encoded by this gene is involved in excision repair and i