Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human DHRS4. AA range:191-240
Subcellular Location
[Isoform 1]: Peroxisome . Isoform 4 is not peroxisomal. .
[Isoform 7]: Nucleus .
[Isoform 7]: Nucleus .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
10901
Observed Band
32-34kD
Other Name
CR
DHRS4
Dehydrogenase/reductase SDR family member 4
NADPH-dependent carbonyl reductase/NADP-retinol dehydrogenase
NADPH-dependent retinol dehydrogenase/reductase
NRDR
PHCR
PSCD
Peroxisomal short-chain alcohol dehydrogenase
humNRDR
DHRS4
Dehydrogenase/reductase SDR family member 4
NADPH-dependent carbonyl reductase/NADP-retinol dehydrogenase
NADPH-dependent retinol dehydrogenase/reductase
NRDR
PHCR
PSCD
Peroxisomal short-chain alcohol dehydrogenase
humNRDR
Background
catalytic activity:R-CHOH-R' + NADP(+) = R-CO-R' + NADPH.,function:Reduces all-trans-retinal and 9-cis retinal. Can also catalyze the oxidation of all-trans-retinol with NADP as co-factor, but with much lower efficiency. Reduces alkyl phenyl ketones and a