Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human DAPK3. AA range:241-290
Subcellular Location
Nucleus . Cytoplasm . Predominantly localizes to the cytoplasm but can shuttle between the nucleus and cytoplasm
[Isoform 1]: Nucleus . Cytoplasm .
[Isoform 2]: Nucleus . Cytoplasm .
cytoplasmic localization is promoted by phosphorylation at Thr-299 and involves Rho/Rock signaling. .
[Isoform 1]: Nucleus . Cytoplasm .
[Isoform 2]: Nucleus . Cytoplasm .
cytoplasmic localization is promoted by phosphorylation at Thr-299 and involves Rho/Rock signaling. .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
1613
Observed Band
52kD
Other Name
DAP-like kinase
DAPK3
DAP kinase 3
Death-associated protein kinase 3
Dlk
MYPT1 kinase
ZIP-kinase
ZIPK
Zipper-interacting protein kinase
DAPK3
DAP kinase 3
Death-associated protein kinase 3
Dlk
MYPT1 kinase
ZIP-kinase
ZIPK
Zipper-interacting protein kinase
Background
Death-associated protein kinase 3 (DAPK3) induces morphological changes in apoptosis when overexpressed in mammalian cells. These results suggest that DAPK3 may play a role in the induction of apoptosis. [provided by RefSeq, Jul 2008],