Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human EIF4G2. AA range:41-90
Subcellular Location
cytosol,cell-cell adherens junction,membrane,eukaryotic translation initiation factor 4F complex,axon,
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Mouse
Human Gen
1982
Observed Band
90kD
Other Name
DAP-5
DAP5
Death-associated protein 5
EIF4G2
Eukaryotic translation initiation factor 4 gamma 2
OK/SW-cl.75
eIF-4-gamma 2
eIF-4G 2
eIF4G 2
p97
DAP5
Death-associated protein 5
EIF4G2
Eukaryotic translation initiation factor 4 gamma 2
OK/SW-cl.75
eIF-4-gamma 2
eIF-4G 2
eIF4G 2
p97
Background
Translation initiation is mediated by specific recognition of the cap structure by eukaryotic translation initiation factor 4F (eIF4F), which is a cap binding protein complex that consists of three subunits: eIF4A, eIF4E and eIF4G. The protein encoded by
eIF4G, in addition, contains a binding site for eIF4E at the N-terminus. Unlike eIF4G, which supports cap-dependent and independent translation, this gene product functions as a general repressor of translation by forming translationally inactive complexe
eIF4G, in addition, contains a binding site for eIF4E at the N-terminus. Unlike eIF4G, which supports cap-dependent and independent translation, this gene product functions as a general repressor of translation by forming translationally inactive complexe