Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human Cytochrome P450 8B1. AA range:371-420
Subcellular Location
Endoplasmic reticulum membrane
Single-pass membrane protein .
Single-pass membrane protein . Microsome membrane
Single-pass membrane protein .
Single-pass membrane protein . Microsome membrane
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Mouse
Human Gen
1582
Observed Band
58kD
Other Name
7-alpha-hydroxy-4-cholesten-3-one 12-alpha-hydroxylase
7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase
CYP8B1
CYP12
CYPVIIIB1
Cytochrome P450 8B1
Sterol 12-alpha-hydroxylase
7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase
CYP8B1
CYP12
CYPVIIIB1
Cytochrome P450 8B1
Sterol 12-alpha-hydroxylase
Background
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic r