Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human Cytochrome P450 27A1. AA range:101-150
Subcellular Location
Mitochondrion inner membrane
Peripheral membrane protein . Post-translationally targeted to mitochondria. All three of the receptor proteins in the TOM complex, TOMM70, TOMM20 and TOMM22 are required for the translocation across the mitochondrial outer membrane. After translocation i
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
1593
Observed Band
60kD
Other Name
5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol 27-hydroxylase
CYP27
CYP27A1
Cytochrome P-450C27/25
Cytochrome P450 27
Sterol 26-hydroxylase
Sterol 27-hydroxylase
Vitamin D(3) 25-hydroxylase
mitochondrial
Background
cytochrome P450 family 27 subfamily A member 1(CYP27A1) Homo sapiens This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and