Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human Cytochrome P450 1A1/2. AA range:71-120
Subcellular Location
Endoplasmic reticulum membrane
Peripheral membrane protein . Cytoplasm .
Peripheral membrane protein . Microsome membrane
Peripheral membrane protein . Mitochondrion inner membrane
Peripheral membrane protein . Cytoplasm .
Peripheral membrane protein . Microsome membrane
Peripheral membrane protein . Mitochondrion inner membrane
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Monkey
Mouse
Rat
Monkey
Mouse
Rat
Human Gen
1543/1544
Observed Band
58kD
Other Name
CYP1A1
CYP1A2
CYPIA1
CYPIA2
Cytochrome P(3)450
Cytochrome P450 1A1
Cytochrome P450 1A2
Cytochrome P450 4
Cytochrome P450 form 6
Cytochrome P450-C
Cytochrome P450-P1
Cytochrome P450-P3
CYP1A2
CYPIA1
CYPIA2
Cytochrome P(3)450
Cytochrome P450 1A1
Cytochrome P450 1A2
Cytochrome P450 4
Cytochrome P450 form 6
Cytochrome P450-C
Cytochrome P450-P1
Cytochrome P450-P3
Background
This gene, CYP1A1, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This prot
however, it is able to metabolize some PAHs to carcinogenic intermediates. The gene has been associated with lung cancer risk. A related family member, CYP1A2, is located approximately 25 kb away from CYP1A1 on chromosome 15. Alternative splicing results
however, it is able to metabolize some PAHs to carcinogenic intermediates. The gene has been associated with lung cancer risk. A related family member, CYP1A2, is located approximately 25 kb away from CYP1A1 on chromosome 15. Alternative splicing results