Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human CSK. AA range:330-379
Subcellular Location
Cytoplasm . Cell membrane . Mainly cytoplasmic, also present in lipid rafts. .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
1445
Observed Band
50kD
Other Name
C-Src kinase
CSK
Protein-tyrosine kinase CYL
Tyrosine-protein kinase CSK
CSK
Protein-tyrosine kinase CYL
Tyrosine-protein kinase CSK
Background
catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.,function:Specifically phosphorylates 'Tyr-504' on LCK, which acts as a negative regulatory site. Can also act on the LYN and FYN kinases.,PTM:Autophosphorylation of