Storage Conditions
-20°C/1 year
Applications
ELISA
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human CPN1. AA range:409-458
Subcellular Location
Secreted, extracellular space.
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
1369
Observed Band
total 52kD,Cleaved 48kD
Other Name
ACBP
Anaphylatoxin inactivator
Arginine carboxypeptidase
CPN
CPN1
Carboxypeptidase N catalytic chain
Carboxypeptidase N polypeptide 1
Carboxypeptidase N small subunit
Kininase-1
Lysine carboxypeptidase
Plasma carboxypeptidase B
S
Background
Carboxypeptidase N is a plasma metallo-protease that cleaves basic amino acids from the C terminal of peptides and proteins. The enzyme is important in the regulation of peptides like kinins and anaphylatoxins, and has also been known as kininase-1 and an
this gene encodes the catalytic subunit. Mutations in this gene can be associated with angioedema or chronic urticaria resulting from carboxypeptidase N deficiency. [provided by RefSeq, Jul 2008],