Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human Cox2. AA range:555-604
Subcellular Location
Microsome membrane
Peripheral membrane protein. Detected on the lumenal side of the endoplasmic reticulum and nuclear envelope. .
Peripheral membrane protein. Endoplasmic reticulum membrane
Peripheral membrane protein. Nucleus inner membrane
Peripheral membrane protein. Nucleus outer membrane
Peripheral membrane protein. Detected on the lumenal side of the endoplasmic reticulum and nuclear envelope. .
Peripheral membrane protein. Endoplasmic reticulum membrane
Peripheral membrane protein. Nucleus inner membrane
Peripheral membrane protein. Nucleus outer membrane
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
5743
Observed Band
70kD
Other Name
COX-2
COX2
Cyclooxygenase-2
PGHS-2
PGH synthase 2
PHS II
PTGS2
Prostaglandin-endoperoxide synthase 2
Prostaglandin G/H synthase 2
Prostaglandin H2 synthase 2
COX2
Cyclooxygenase-2
PGHS-2
PGH synthase 2
PHS II
PTGS2
Prostaglandin-endoperoxide synthase 2
Prostaglandin G/H synthase 2
Prostaglandin H2 synthase 2
Background
Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, whi