Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human Cofilin. AA range:1-50
Subcellular Location
Cytoplasmic side . Cell projection, lamellipodium . Cell projection, growth cone . Cell projection, axon . Colocalizes with the actin cytoskeleton in membrane ruffles and lamellipodia. Detected at the cleavage furrow and contractile ring during cytokinesi
Cytoplasmic side . Cell projection, lamellipodium membrane
Nucleus matrix . Cytoplasm, cytoskeleton . Cell projection, ruffle membrane
Peripheral membrane protein
Peripheral membrane protein
Cytoplasmic side . Cell projection, lamellipodium membrane
Nucleus matrix . Cytoplasm, cytoskeleton . Cell projection, ruffle membrane
Peripheral membrane protein
Peripheral membrane protein
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
1072
Observed Band
19kD
Other Name
18 kDa phosphoprotein
CFL
CFL1
Cofilin
Cofilin-1
non-muscle isoform
p18
CFL
CFL1
Cofilin
Cofilin-1
non-muscle isoform
p18
Background
cofilin 1(CFL1) Homo sapiens The protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a pH-dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganization of the actin cytoskel