Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human Clock. AA range:241-290
Subcellular Location
Nucleus . Cytoplasm . Cytoplasm, cytosol . Shuttling between the cytoplasm and the nucleus is under circadian regulation and is ARNTL/BMAL1-dependent. Phosphorylated form located in the nucleus while the nonphosphorylated form found only in the cytoplasm.
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
9575
Observed Band
95kD
Other Name
BHLHE8
CLOCK
Circadian locomoter output cycles protein kaput
Class E basic helix-loop-helix protein 8
KIAA0334
bHLHe8
hCLOCK
CLOCK
Circadian locomoter output cycles protein kaput
Class E basic helix-loop-helix protein 8
KIAA0334
bHLHe8
hCLOCK
Background
The protein encoded by this gene plays a central role in the regulation of circadian rhythms. The protein encodes a transcription factor of the basic helix-loop-helix (bHLH) family and contains DNA binding histone acetyltransferase activity. The encoded p