Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human CLK2. AA range:1-50
Subcellular Location
Nucleus .
[Isoform 1]: Nucleus . Nucleus speckle . Inhibition of phosphorylation at Ser-142 results in accumulation in the nuclear speckle. .
[Isoform 2]: Nucleus speckle . Co-localizes with serine- and arginine-rich (SR) proteins in the nuclear speckles. .
[Isoform 1]: Nucleus . Nucleus speckle . Inhibition of phosphorylation at Ser-142 results in accumulation in the nuclear speckle. .
[Isoform 2]: Nucleus speckle . Co-localizes with serine- and arginine-rich (SR) proteins in the nuclear speckles. .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
1196
Observed Band
60kD
Other Name
CDC-like kinase 2
CLK2
Dual specificity protein kinase CLK2
CLK2
Dual specificity protein kinase CLK2
Background
CDC like kinase 2(CLK2) Homo sapiens This gene encodes a dual specificity protein kinase that phosphorylates serine/threonine and tyrosine-containing substrates. Activity of this protein regulates serine- and arginine-rich (SR) proteins of the spliceos