Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human Claudin 4. AA range:160-209
Subcellular Location
Cell junction, tight junction . Cell membrane
Multi-pass membrane protein . CLDN4 is required for tight junction localization in the kidney. .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
1364
Observed Band
22kD
Other Name
CLDN4
CPE-R
CPE-receptor
CPER
CPETR1
Claudin-4
Clostridium perfringens enterotoxin receptor
WBSCR8
Williams-Beuren syndrome chromosomal region 8 protein
Background
The protein encoded by this intronless gene belongs to the claudin family. Claudins are integral membrane proteins that are components of the epithelial cell tight junctions, which regulate movement of solutes and ions through the paracellular space. This