Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human Chr-A. AA range:311-360
Subcellular Location
Cytoplasmic vesicle, secretory vesicle . Cytoplasmic vesicle, secretory vesicle, neuronal dense core vesicle . Secreted . Associated with the secretory granule membrane through direct interaction to SCG3 that in turn binds to cholesterol-enriched lipid ra
[Serpinin]: Secreted . Cytoplasmic vesicle, secretory vesicle . Pyroglutaminated serpinin localizes to secretory vesicle. .
[Serpinin]: Secreted . Cytoplasmic vesicle, secretory vesicle . Pyroglutaminated serpinin localizes to secretory vesicle. .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
1113
Observed Band
68kD
Other Name
CHGA
CgA
Chromogranin-A
Pituitary secretory protein I
SP-I
CgA
Chromogranin-A
Pituitary secretory protein I
SP-I
Background
The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. It is found in secretory vesicles of neurons and endocrine cells. This gene product is a precursor to three biologically active pep
vasostatin, pancreastatin, and parastatin. These peptides act as autocrine or paracrine negative modulators of the neuroendocrine system. Two other peptides, catestatin and chromofungin, have antimicrobial activity and antifungal activity, respectively. T
vasostatin, pancreastatin, and parastatin. These peptides act as autocrine or paracrine negative modulators of the neuroendocrine system. Two other peptides, catestatin and chromofungin, have antimicrobial activity and antifungal activity, respectively. T