Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human CHOP. AA range:15-64
Subcellular Location
Cytoplasm . Nucleus . Present in the cytoplasm under non-stressed conditions and ER stress leads to its nuclear accumulation. .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Human Gen
1649
Observed Band
19kD
Other Name
C/EBP-homologous protein
C/EBP-homologous protein 10
CHOP
CHOP
CHOP-10
CHOP10
DDIT-3
DDIT3
DNA damage-inducible transcript 3 protein
GADD153
Growth arrest and DNA damage-inducible protein GADD153
Background
This gene encodes a member of the CCAAT/enhancer-binding protein (C/EBP) family of transcription factors. The protein functions as a dominant-negative inhibitor by forming heterodimers with other C/EBP members, such as C/EBP and LAP (liver activator prote