Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human FAS. AA range:281-330
Subcellular Location
Single-pass type I membrane protein . Membrane raft .
[Isoform 1]: Cell membrane
[Isoform 2]: Secreted.
[Isoform 3]: Secreted.
[Isoform 4]: Secreted.
[Isoform 5]: Secreted.
[Isoform 6]: Secreted.
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
355
Observed Band
50kD
Other Name
APT1
Apo-1 antigen
Apoptosis-mediating surface antigen FAS
CD antigen CD95
FAS
FAS1
FASLG receptor
TNFRSF6
Tumor necrosis factor receptor superfamily member 6
Background
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains a death domain. It has been shown to play a central role in the physiological regulation of programmed cell death, and has been implicated in the pathogen