Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
WB
IF
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human CCRL1. AA range:291-340
Subcellular Location
Early endosome . Recycling endosome . Cell membrane
Multi-pass membrane protein . Predominantly localizes to endocytic vesicles, and upon stimulation by the ligand is internalized via caveolae. Once internalized, the ligand dissociates from the receptor, and is targeted to degradation while the receptor is
Multi-pass membrane protein . Predominantly localizes to endocytic vesicles, and upon stimulation by the ligand is internalized via caveolae. Once internalized, the ligand dissociates from the receptor, and is targeted to degradation while the receptor is
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Mouse
Human Gen
51554
Observed Band
40kD
Other Name
C-C CKR-11
C-C chemokine receptor type 11
CC-CKR-11
CCBP2
CCR-11
CCR11
CCRL1
CCRL1
CCX CKR
CC chemokine receptor-like 1
VSHK1
C-C chemokine receptor type 11
CC-CKR-11
CCBP2
CCR-11
CCR11
CCRL1
CCRL1
CCX CKR
CC chemokine receptor-like 1
VSHK1
Background
The protein encoded by this gene is a member of the G protein-coupled receptor family, and is a receptor for C-C type chemokines. This receptor has been shown to bind dendritic cell- and T cell-activated chemokines including CCL19/ELC, CCL21/SLC, and CCL2