Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human NCBP1. AA range:1-50
Subcellular Location
Nucleus . Cytoplasm . Localized in cytoplasmic mRNP granules containing untranslated mRNAs. .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
4686
Observed Band
80kD
Other Name
80 kDa nuclear cap-binding protein
CBP80
CBP80
NCBP
NCBP1
NCBP 80 kDa subunit
Nuclear cap-binding protein subunit 1
Background
The product of this gene is a component of the nuclear cap-binding protein complex (CBC), which binds to the monomethylated 5' cap of nascent pre-mRNA in the nucleoplasm. The encoded protein promotes high-affinity mRNA-cap binding and associates with the