Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human Galectin 3. AA range:141-190
Subcellular Location
Cytoplasm . Nucleus. Secreted . Secreted by a non-classical secretory pathway and associates with the cell surface. Can be secreted
it results in protein translocation from the cytoplasm into the ERGIC (endoplasmic reticulum-Golgi intermediate compartment) followed by vesicle entry and secretion (PubMed:32272059). .
the secretion is dependent on protein unfolding and facilitated by the cargo receptor TMED10
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
3958
Observed Band
33kD
Other Name
35 kDa lectin
CBP 35
Carbohydrate-binding protein 35
GALBP
Gal-3
Galactose-specific lectin 3
Galactoside-binding protein
Galectin-3
IgE-binding protein
L-31
LGALS3
Laminin-binding protein
Lectin L-29
MAC2
Mac-2 antigen
Background
This gene encodes a member of the galectin family of carbohydrate binding proteins. Members of this protein family have an affinity for beta-galactosides. The encoded protein is characterized by an N-terminal proline-rich tandem repeat domain and a single