Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human CBL. AA range:740-789
Subcellular Location
Cytoplasm. Cell membrane. Cell projection, cilium . Golgi apparatus . Colocalizes with FGFR2 in lipid rafts at the cell membrane.
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
867
Observed Band
100kD
Other Name
CBL
CBL2
Casitas B-lineage lymphoma proto-oncogene
E3 ubiquitin-protein ligase CBL
Proto-oncogene c-Cbl
RING finger protein 55
RNF55
Signal transduction protein CBL
CBL2
Casitas B-lineage lymphoma proto-oncogene
E3 ubiquitin-protein ligase CBL
Proto-oncogene c-Cbl
RING finger protein 55
RNF55
Signal transduction protein CBL
Background
Cbl proto-oncogene(CBL) Homo sapiens This gene is a proto-oncogene that encodes a RING finger E3 ubiquitin ligase. The encoded protein is one of the enzymes required for targeting substrates for degradation by the proteasome. This protein mediates the