Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human Cathepsin B. AA range:168-217
Subcellular Location
Extracellular side . Identified by mass spectrometry in melanosome fractions from stage I to stage IV (PubMed:17081065). Localizes to the lumen of thyroid follicles and to the apical membrane of thyroid epithelial cells (By similarity). .
Lysosome . Melanosome . Secreted, extracellular space . Apical cell membrane
Peripheral membrane protein
Lysosome . Melanosome . Secreted, extracellular space . Apical cell membrane
Peripheral membrane protein
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
1508
Observed Band
38,40,25kD
Other Name
APPS
APP secretase
CPSB
CTSB
Cathepsin B
Cathepsin B1
APP secretase
CPSB
CTSB
Cathepsin B
Cathepsin B1
Background
This gene encodes a member of the C1 family of peptidases. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate multiple protein pro