Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human Caspase 10. AA range:430-479
Subcellular Location
cytosol,CD95 death-inducing signaling complex,ripoptosome,
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
843
Observed Band
pro: 60kD, actived: 33kD 12kD
Other Name
ALPS2
CASP-10
CASPA
FADD-like ICE2
FAS-associated death domain protein interleukin-1B-convert
apoptotic protease Mch-4
caspase-10
Background
This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo pro