Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
IP
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunoprecipitation: 2-5 ug/mg lysate. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human CSE1L. AA range:1-50
Subcellular Location
Cytoplasm . Nucleus . Shuttles between the nucleus and the cytoplasm. .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
1434
Observed Band
110kD
Other Name
CAS
CSE1L
Cellular apoptosis susceptibility protein
Chromosome segregation 1-like protein
Exp2
Exportin-2
Importin-alpha re-exporter
XPO2
Background
Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation