Storage Conditions
-20°C/1 year
Applications
ELISA
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human CXADR. AA range:1-50
Subcellular Location
Single-pass type I membrane protein . Basolateral cell membrane
Single-pass type I membrane protein . Cell junction, tight junction . Cell junction, adherens junction . In epithelial cells localizes to the apical junction complex composed of tight and adherens junctions (PubMed:12297051). In airway epithelial cells lo
[Isoform 1]: Cell membrane
[Isoform 3]: Secreted .
[Isoform 4]: Secreted .
[Isoform 5]: Secreted .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
1525
Observed Band
40kD
Other Name
CAR
CAR
CVB3-binding protein
CXADR
Coxsackievirus B-adenovirus receptor
Coxsackievirus and adenovirus receptor
HCVADR
hCAR
Background
The protein encoded by this gene is a type I membrane receptor for group B coxsackieviruses and subgroup C adenoviruses. Several transcript variants encoding different isoforms have been found for this gene. Pseudogenes of this gene are found on chromosom