Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human Ik3-1. AA range:561-610
Subcellular Location
Nucleus . Cytoplasm . Located in the cell body and proximal region of the developing axonal shaft of immature neurons. Located in axonal growth cone, but not in the distal part of the axon shaft or in dendritic growth cone of mature neurons (By similarity
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Mouse
Human Gen
91768
Observed Band
67kD
Other Name
CABLES
CABLES1
CDK5 and ABL1 enzyme substrate 1
Ik3-1
Interactor with CDK3 1
CABLES1
CDK5 and ABL1 enzyme substrate 1
Ik3-1
Interactor with CDK3 1
Background
This gene encodes a protein involved in regulation of the cell cycle through interactions with several cyclin-dependent kinases. One study (PMID: 16177568) reported aberrant splicing of transcripts from this gene which results in removal of the cyclin bin