Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
WB
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human BUB1B. AA range:341-390
Subcellular Location
Cytoplasm. Nucleus. Chromosome, centromere, kinetochore. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasmic in interphase cells. Associates with the kinetochores in early prophase. Kinetochore localization requires BUB1, PLK1
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Mouse
Human Gen
701
Observed Band
130kD
Other Name
BUB1B
BUBR1
MAD3/BUB1-related protein kinase
MAD3L
Mitotic checkpoint kinase MAD3L
Mitotic checkpoint serine/threonine-protein kinase BUB1 beta
Protein SSK1
SSK1
hBUBR1
BUBR1
MAD3/BUB1-related protein kinase
MAD3L
Mitotic checkpoint kinase MAD3L
Mitotic checkpoint serine/threonine-protein kinase BUB1 beta
Protein SSK1
SSK1
hBUBR1
Background
This gene encodes a kinase involved in spindle checkpoint function. The protein has been localized to the kinetochore and plays a role in the inhibition of the anaphase-promoting complex/cyclosome (APC/C), delaying the onset of anaphase and ensuring prope