Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human BLNK. AA range:62-111
Subcellular Location
Cytoplasm . Cell membrane . BCR activation results in the translocation to membrane fraction.
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Human Gen
29760
Observed Band
50kD
Other Name
B-cell adapter containing a SH2 domain protein
B-cell adapter containing a Src homology 2 domain protein
B-cell linker protein
BASH
BLNK
Cytoplasmic adapter protein
SLP65
Src homology 2 domain-containing leukocyte protein of 65 kDa
Background
This gene encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. This protein bridges B cell receptor-associated kinase activation with downstream signaling pathways, thereby affecting various biological function