Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human BIM. AA range:1-50
Subcellular Location
Endomembrane system
Peripheral membrane protein . Associated with intracytoplasmic membranes. .
[Isoform Bim-alpha1]: Mitochondrion.
[Isoform BimEL]: Mitochondrion. Translocates from microtubules to mitochondria on loss of cell adherence.
[Isoform BimL]: Mitochondrion.
[Isoform BimS]: Mitochondrion.
Peripheral membrane protein . Associated with intracytoplasmic membranes. .
[Isoform Bim-alpha1]: Mitochondrion.
[Isoform BimEL]: Mitochondrion. Translocates from microtubules to mitochondria on loss of cell adherence.
[Isoform BimL]: Mitochondrion.
[Isoform BimS]: Mitochondrion.
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Monkey
Mouse
Rat
Monkey
Mouse
Rat
Human Gen
10018
Observed Band
22kD
Other Name
BCL2L11
BIM
Bcl-2-like protein 11
Bcl2-L-11
Bcl2-interacting mediator of cell death
BIM
Bcl-2-like protein 11
Bcl2-L-11
Bcl2-interacting mediator of cell death
Background
The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The protein encoded by this gene