Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human ARFGEF2. AA range:1491-1540
Subcellular Location
Cytoplasm. Membrane. Golgi apparatus. Cytoplasm, perinuclear region. Golgi apparatus, trans-Golgi network . Endosome . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cell projection, dendrite . Cytoplasmic vesicle . Cell junction, syn
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
10564
Observed Band
210kD
Other Name
ADP-ribosylation factor guanine nucleotide-exchange factor 2
ARFGEF2
ARFGEP2
BIG2
Brefeldin A-inhibited GEP 2
Brefeldin A-inhibited guanine nucleotide-exchange protein 2
ARFGEF2
ARFGEP2
BIG2
Brefeldin A-inhibited GEP 2
Brefeldin A-inhibited guanine nucleotide-exchange protein 2
Background
ADP-ribosylation factors (ARFs) play an important role in intracellular vesicular trafficking. The protein encoded by this gene is involved in the activation of ARFs by accelerating replacement of bound GDP with GTP and is involved in Golgi transport. It