Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human FGFR2. AA range:471-520
Subcellular Location
Cell membrane
Single-pass type I membrane protein. After ligand binding, the activated receptor is rapidly internalized and degraded.
Single-pass type I membrane protein. After ligand binding, the activated receptor is rapidly internalized and degraded.
Single-pass type I membrane protein. Golgi apparatus. Cytoplasmic vesicle. Detected on osteoblast plasma membrane lipid rafts. After ligand binding, the activated receptor is rapidly internalized and degraded.
[Isoform 1]: Cell membrane
[Isoform 3]: Cell membrane
[Isoform 8]: Secreted.
[Isoform 13]: Secreted.
Single-pass type I membrane protein. After ligand binding, the activated receptor is rapidly internalized and degraded.
Single-pass type I membrane protein. After ligand binding, the activated receptor is rapidly internalized and degraded.
Single-pass type I membrane protein. Golgi apparatus. Cytoplasmic vesicle. Detected on osteoblast plasma membrane lipid rafts. After ligand binding, the activated receptor is rapidly internalized and degraded.
[Isoform 1]: Cell membrane
[Isoform 3]: Cell membrane
[Isoform 8]: Secreted.
[Isoform 13]: Secreted.
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
2263
Observed Band
120kD
Other Name
BEK
CD antigen CD332
FGFR-2
FGFR2
Fibroblast growth factor receptor 2
K-sam
KGFR
KGFR
KSAM
Keratinocyte growth factor receptor
CD antigen CD332
FGFR-2
FGFR2
Fibroblast growth factor receptor 2
K-sam
KGFR
KGFR
KSAM
Keratinocyte growth factor receptor
Background
The protein encoded by this gene is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities an