Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human AurB/C. AA range:201-250
Subcellular Location
Nucleus . Chromosome . Chromosome, centromere . Chromosome, centromere, kinetochore . Cytoplasm, cytoskeleton, spindle . Midbody . Localizes on chromosome arms and inner centromeres from prophase through metaphase and then transferring to the spindle midz
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
9212/6795
Observed Band
35+39kD
Other Name
AIK2
AIM-1
AIM1
AIRK2
ARK-2
ARK2
AURKB
Aurora- and IPL1-like midbody-associated protein 1
Aurora-related kinase 2
Aurora/IPL1-related kinase 2
Aurora 1
Aurora kinase B
STK-1
STK1
STK5
STK12
Serine/threonine-protein kinase 12
Background
This gene encodes a member of the aurora kinase subfamily of serine/threonine kinases. The genes encoding the other two members of this subfamily are located on chromosomes 19 and 20. These kinases participate in the regulation of alignment and segregatio