Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
FCM
IF
IHC
WB
FCM
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. Flow cytometry: 1/200 - 1/400. ELISA: 1/5000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human Adrenergic Receptor beta2. AA range:321-370
Subcellular Location
Cell membrane
Multi-pass membrane protein . Early endosome . Golgi apparatus . Colocalizes with VHL at the cell membrane (PubMed:19584355). Activated receptors are internalized into endosomes prior to their degradation in lysosomes (PubMed:20559325). Activated receptor
Multi-pass membrane protein . Early endosome . Golgi apparatus . Colocalizes with VHL at the cell membrane (PubMed:19584355). Activated receptors are internalized into endosomes prior to their degradation in lysosomes (PubMed:20559325). Activated receptor
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
154
Observed Band
47kD
Other Name
ADRB2
ADRB2R
B2AR
Beta-2 adrenergic receptor
Beta-2 adrenoceptor
Beta-2 adrenoreceptor
ADRB2R
B2AR
Beta-2 adrenergic receptor
Beta-2 adrenoceptor
Beta-2 adrenoreceptor
Background
This gene encodes beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel compl