Storage Conditions
-20°C/1 year
Applications
ELISA
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human APPL1. AA range:121-170
Subcellular Location
Early endosome membrane
Peripheral membrane protein . Nucleus . Cytoplasm . Endosome . Cell projection, ruffle . Cytoplasmic vesicle, phagosome . Early endosomal membrane-bound and nuclear. Translocated into the nucleus upon release from endosomal membranes following internaliza
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Human Gen
26060
Observed Band
80kD
Other Name
APPL
APPL1
Adapter protein containing PH domain
DCC-interacting protein 13-alpha
DIP13A
Dip13-alpha
KIAA1428
PTB domain and leucine zipper motif 1
Background
adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1(APPL1) Homo sapiens The protein encoded by this gene has been shown to be involved in the regulation of cell proliferation, and in the crosstalk between the adiponectin si