Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human API-5. AA range:421-470
Subcellular Location
Nucleus . Cytoplasm . Mainly nuclear. Can also be cytoplasmic.
[Isoform 3]: Cytoplasm.
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Human Gen
8539
Observed Band
58kD
Other Name
AAC-11
API-5
API5
Antiapoptosis clone 11 protein
Apoptosis inhibitor 5
Cell migration-inducing gene 8 protein
FIF
Fibroblast growth factor 2-interacting factor
MIG8
Protein XAGL
Background
This gene encodes an apoptosis inhibitory protein whose expression prevents apoptosis after growth factor deprivation. This protein suppresses the transcription factor E2F1-induced apoptosis and also interacts with, and negatively regulates Acinus, a nucl