Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human AIFM1. AA range:51-100
Subcellular Location
Mitochondrion intermembrane space . Mitochondrion inner membrane. Cytoplasm . Nucleus . Cytoplasm, perinuclear region . Proteolytic cleavage during or just after translocation into the mitochondrial intermembrane space (IMS) results in the formation of an
[Isoform 3]: Mitochondrion intermembrane space . Mitochondrion inner membrane . Has a stronger membrane ancho
[Isoform 3]: Mitochondrion intermembrane space . Mitochondrion inner membrane . Has a stronger membrane ancho
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
9131
Observed Band
67kD
Other Name
AIF
AIFM1
Apoptosis-inducing factor 1
PDCD8
Programmed cell death protein 8
mitochondrial
AIFM1
Apoptosis-inducing factor 1
PDCD8
Programmed cell death protein 8
mitochondrial
Background
This gene encodes a flavoprotein essential for nuclear disassembly in apoptotic cells, and it is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it a