Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human ADARB1. AA range:481-530
Subcellular Location
Nucleus . Nucleus, nucleolus . Shuttles between nucleoli and the nucleoplasm. .
[Isoform 1]: Nucleus . Nucleus, nucleolus .
[Isoform 2]: Nucleus . Nucleus, nucleolus .
[Isoform 1]: Nucleus . Nucleus, nucleolus .
[Isoform 2]: Nucleus . Nucleus, nucleolus .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
104
Observed Band
80kD
Other Name
ADAR2
ADARB1
DRADA2
Double-stranded RNA-specific editase 1
RED1
RNA-editing deaminase 1
RNA-editing enzyme 1
dsRNA adenosine deaminase
ADARB1
DRADA2
Double-stranded RNA-specific editase 1
RED1
RNA-editing deaminase 1
RNA-editing enzyme 1
dsRNA adenosine deaminase
Background
This gene encodes the enzyme responsible for pre-mRNA editing of the glutamate receptor subunit B by site-specific deamination of adenosines. Studies in rat found that this enzyme acted on its own pre-mRNA molecules to convert an AA dinucleotide to an AI