Información del producto
Actinin-α1/2/3/4 rabbit pAb
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human ACTN1/2/3/4. AA range:21-70
Subcellular Location
Cytoplasm, cytoskeleton . Cytoplasm, myofibril, sarcomere, Z line . Cell membrane . Cell junction . Cell projection, ruffle . Colocalizes with MYOZ2 and PPP3CA at the Z-line of heart and skeletal muscle. Colocalizes with PSD in membrane ruffles and centra
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
87/88/89/81
Observed Band
75kD
Other Name
A
ACTN1
ACTN2
ACTN3
Alpha-actinin-1
Alpha-actinin-2
Alpha-actinin-3
Alpha-actinin cytoskeletal isoform
Alpha-actinin skeletal muscle isoform 2
F-actin cross-linking protein
F-actin cross-linking protein
Non-muscle alpha-actinin-1
ACTN1
ACTN2
ACTN3
Alpha-actinin-1
Alpha-actinin-2
Alpha-actinin-3
Alpha-actinin cytoskeletal isoform
Alpha-actinin skeletal muscle isoform 2
F-actin cross-linking protein
F-actin cross-linking protein
Non-muscle alpha-actinin-1
Background
Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types