Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human ACOT8. AA range:131-180
Subcellular Location
Peroxisome matrix . Predominantly localized in the peroxisome but a localization to the cytosol cannot be excluded. .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
10005
Observed Band
36kD
Other Name
ACOT8
ACTEIII
Acyl-CoA thioesterase 8
Acyl-coenzyme A thioesterase 8
Choloyl-coenzyme A thioesterase
HIV-Nef-associated acyl-CoA thioesterase
PTE-1
PTE-2
PTE1
PTE2
Peroxisomal acyl-coenzyme A thioester hydrolase 1
Peroxisomal lon
Background
The protein encoded by this gene is a peroxisomal thioesterase that appears to be involved more in the oxidation of fatty acids rather than in their formation. The encoded protein can bind to the human immunodeficiency virus-1 protein Nef, and mediate Nef