Storage Conditions
-20°C/1 year
Applications
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
IHC-p 1:50-300
WB 1:500-2000
Type Clonality
Polyclonal
Immunogen
Synthesized phospho-peptide around the phosphorylation site of human MLK3 (phospho Ser674)
Subcellular Location
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Location is cell cycle dependent.
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
4296
Other Name
MAP3K11
MLK3
Mitogen-activated protein kinase kinase kinase 11
Mixed lineage kinase 3
PTK1
SPRK
Src-homology 3 domain-containing proline-rich kinase
Background
The protein encoded by this gene is a member of the serine/threonine kinase family. This kinase contains a SH3 domain and a leucine zipper-basic motif. This kinase preferentially activates MAPK8/JNK kinase, and functions as a positive regulator of JNK sig