Storage Conditions
-20°C/1 year
Applications
ELISA
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
Synthesized phospho-peptide around the phosphorylation site of human Ob-R (phospho Tyr1141)
Subcellular Location
Cell membrane
Single-pass type I membrane protein . Basolateral cell membrane .
[Isoform E]: Secreted .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Human Gen
3953
Observed Band
132kD
Other Name
CD antigen CD295
DB
HuB219
LEP-R
LEPR
Leptin receptor
OB-R
OBR
OB receptor
Background
The protein encoded by this gene belongs to the gp130 family of cytokine receptors that are known to stimulate gene transcription via activation of cytosolic STAT proteins. This protein is a receptor for leptin (an adipocyte-specific hormone that regulate