Storage Conditions
-20°C/1 year
Applications
ELISA
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
Synthesized phospho-peptide around the phosphorylation site of human Flt-1 (phospho Tyr1213)
Subcellular Location
Single-pass type I membrane protein. Endosome. Autophosphorylation promotes ubiquitination and endocytosis.
[Isoform 1]: Cell membrane
[Isoform 2]: Secreted .
[Isoform 3]: Secreted.
[Isoform 4]: Secreted.
[Isoform 5]: Cytoplasm .
[Isoform 6]: Cytoplasm .
[Isoform 7]: Cytoplasm .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
2321
Observed Band
150kD
Other Name
FLT
FLT
FLT-1
FLT1
FRT
Fms-like tyrosine kinase 1
Tyrosine-protein kinase FRT
Tyrosine-protein kinase receptor FLT
VEGFR-1
VEGFR1
Vascular endothelial growth factor receptor 1
Vascular permeability factor receptor
Background
This gene encodes a member of the vascular endothelial growth factor receptor (VEGFR) family. VEGFR family members are receptor tyrosine kinases (RTKs) which contain an extracellular ligand-binding region with seven immunoglobulin (Ig)-like domains, a tra