Información del producto
DARPP-32 (phospho Thr34) rabbit pAb
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human DARPP-32 around the phosphorylation site of Thr34. AA range:18-67
Subcellular Location
Cytoplasm.
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
84152
Observed Band
35kD
Other Name
DARPP-32
DARPP32
Dopamine- and cAMP-regulated neuronal phosphoprotein
PPP1R1B
Protein phosphatase 1 regulatory subunit 1B
DARPP32
Dopamine- and cAMP-regulated neuronal phosphoprotein
PPP1R1B
Protein phosphatase 1 regulatory subunit 1B
Background
This gene encodes a bifunctional signal transduction molecule. Dopaminergic and glutamatergic receptor stimulation regulates its phosphorylation and function as a kinase or phosphatase inhibitor. As a target for dopamine, this gene may serve as a therapeu